A benzimidazole-derived fluorescent chemosensor for Cu(II)-selective turn-off and Zn(II)-selective ratiometric turn-on detection in aqueous solutions
作者：Wan-Yu Zhu, Kai Liu, XuanZhang
關(guān)鍵字：fluorescent chemosensor, Cu(II) , Zn(II)
論文來源：期刊
具體來源：Sensors and Diagnostics, 2023, 2(3), 665–675
發(fā)表時(shí)間：2023年
A 2,6-dibenzoimidazolyl-4-methoxyphenol conjugate (BBMP) was designed and synthesized to develop a novel fluorescent chemosensor for Cu2+ and Zn2+. The as-fabricated BBMP showed an excited-state intramolecular proton-transfer (ESIPT) fluorescence emission at 542 nm that was selectively and efficiently quenched by Cu2+ in a Tris-HCl solution (70% THF, pH = 7.4) due to the inhibition of ESIPT upon binding to metal ions. In contrast, the addition of Zn2+ not only resulted in a substantial decline in the original ESIPT fluorescence of BBMP but was also accompanied by the appearance of a new blue fluorescence emission at 462 nm. This indicated the potential for the present BBMP as a novel fluorescent probe for Cu2+ (turn-off) and Zn2+ (ratiometric turn-on) detection in aqueous solutions. The linear range and detection limit were found to be 0–5 μM and 0.16 μM for Cu2+, as well as 0–10 μM and 0.1 μM for Zn2+, respectively. A 2?:?1/1?:?1 coordination mode between BBMP and Cu2+/Zn2+ was confirmed by Job plots and mass analysis. Potential practical applications were also demonstrated by the analysis of real water samples and living cell imaging.