發明/申請人：楊 光，王剛，劉筆鋒，史續典，陳旭峰
專利號/申請號：ZL 200810047875.1
授權/申請日期：2011-3-24
本發明提供了一種通過微流控芯片制備圖案化纖維素的方法，按照以下步驟進行：（1）依據預定圖案制作陽膜；（2）制備與陽膜圖案相匹配的聚二甲基硅氧烷(PDMS)模塊；（3）在PDMS模塊上打孔，將潔凈的載玻片壓緊于PDMS模塊有圖案的一面，形成微流控芯片，其中PDMS模塊上的圖案化管道通過孔與外界相連通；（4）在兩儲液槽中裝入細菌培養液，利用導管將微流控芯片的圖案化管道分別與兩儲液槽連通，調節兩儲液槽之間的液面差控制圖案化管道內的液體流速，其液面差為1-20cm，培養5-20天，揭開PDMS模塊，得到圖案化纖維素。采用本發明制得的細菌纖維素材料具有微觀的有序性和宏觀的圖案性，并兼有生物相容性和生態相容性，是理想的環境友好材料。
ABSTRACT:
NOVELTY - Patterning cellulose is prepared by perforating polydimethyl silicone (PDMS) module matching with the anode film patterns; placing bacterial culture solution to liquid tanks and culturing 5-20 days; and removing the PDMS module to obtain the patterning cellulose. The PDMS is perforated by compressing a clean glass slide on one surface of the PDMS module having the patterns to form the microfluidic chip.
USE - Method for preparing patterning cellulose (claimed).
ADVANTAGE - The prepared bacteria cellulose material comprises microcosmic sequence and macroscopic patterning performance, and biocompatibility and ecology compatibility; and is perfect environment-friendly material.
