 | 濉戞枡 | 姍¤兌 | 綰ょ淮 | 娑傛枡涓庢補澧?/a> | 鑳剁矘鍓?/a> | 澶嶅悎鏉愭枡 | 鐭沖寲 | 鍖栧伐 | 浠櫒浠〃 | 鏂頒駭涓?/a> | 涓撻 | 榪斿洖棣栭〉 |
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| 濉戞枡 | 姍¤兌 | 綰ょ淮 | 娑傛枡涓庢補澧?/a> | 鑳剁矘鍓?/a> | 澶嶅悎鏉愭枡 | 鐭沖寲 | 鍖栧伐 | 浠櫒浠〃 | 鏂頒駭涓?/a> | 涓撻 | 榪斿洖棣栭〉 |
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緇嗚弻鐢熺墿鑶滃紩璧風殑浼ゅ彛鎰熸煋涓鐩翠互鏉ュ▉鑳佺潃浜虹被鐨勫仴搴鳳紝騫跺彲寮曡搗杈冮珮鐨勬浜＄巼銆傝繎騫存潵錛岀撼綾蟲姉鑿屾潗鏂欏湪浼ゅ彛鎰堝悎鐨勫簲鐢ㄦ垚涓轟簡鐮旂┒鐒︾偣錛屽叾涓熀浜庡偓鍖栨椿鎬х殑綰崇背鎶楄弻鏉愭枡澶囧彈鍏蟲敞銆傜劧鑰岋紝緇嗚弻鐢熺墿鑶滃井鐜涓殑鍐呮簮鎬?/span>H2O2鍚噺杈冧綆錛岄檺鍒朵簡鎶楄弻鍓傜殑鍌寲媧繪э紝娣誨姞澶栨簮鎬?/span>H2O2鍗村張浼氬浼ゅ彛鍛ㄥ洿鐨勫仴搴風粏鑳炵粍緇囦駭鐢熷壇浣滅敤銆傚洜姝わ紝鍦ㄦ彁楂樻姉鑿屽墏鐨勬姉鑿屼綔鐢ㄧ殑鍚屾椂灝藉彲鑳借閬垮壇浣滅敤錛岃繖浠嶆槸涓涓法澶х殑鎸戞垬銆?/span>
榪戞棩錛?/span>瑗垮寳鍐滄灄縐戞妧澶у鐜嬪緩榫欐暀鎺?/span>璇鵑緇?/span>鍦ㄣ?/span>ACS Applied Materials & Interfaces銆嬫湡鍒婁笂鍙戣〃浜嗛涓?/span>鈥?/span>Acid-Induced Self-Catalyzing Platform Based on Dextran-Coated Copper Peroxide Nanoaggregates for Biofilm Treatment鈥?span style="font-family:瀹嬩綋;">鐨勬枃绔狅紙DOI: 10.1021/acsami.1c03409錛夈傝鏂囩珷璁捐浜?/span>鍩轟簬钁¤仛緋栧寘瑕嗙殑榪囨哀鍖栭摐綰崇背鑱氶泦浣撶殑閰告ц瀵艱嚜鍌寲騫沖彴錛?/span>DCPNAs錛夛紝騫墮嬈″皢涔欓唶娌夋穩娉曡繍鐢ㄤ簬鍩轟簬澶氱硸鐨勫皬綺掑緞綰崇背棰楃矑鐨勭函鍖栥傛澶栵紝璇鵑緇勯拡瀵硅鑷偓鍖栧鉤鍙扮殑閰告ц瀵肩殑鎶楄弻銆佹姉鐢熺墿鑶滄ц兘榪涜浜嗗叏闈㈣屾繁鍏ョ殑鐮旂┒錛屽茍灝嗗叾搴旂敤浜庨噾榛勮壊钁¤悇鐞冭弻鎰熸煋浼ゅ彛鐨勬不鐤椼?br />
Scheme 1. (a) DCPNAs閫氳繃閰歌瀵奸噴鏀?/span>ROS鐨勬姉鐢熺墿鑶滄ц兘紺烘剰鍥撅紱(b) 浣跨敤鍏鋒湁浼ゅ彛鐨偆鐨勫皬榧犱綔涓烘劅鏌撲激鍙ｆā鍨嬪DCPNAs榪涜浣撳唴鎶楃敓鐗╄啘鐮旂┒鐨勭ず鎰忓浘
Figure 1. (a) DCPNAs鍚堟垚紺烘剰鍥撅紱(b) 浠ヤ笉鍚岀殑OH-涓?/span>Cu2 鎽╁皵姣斿悎鎴愮殑DCPNAs鐨勭収鐗?/span>
錛?/span>(A) 0:1錛?/span>(B) 1:2錛?/span>(C) 1:1錛?/span>(D) 2:1錛?/span>(c) DCPNAs鐨?/span>TEM鍥懼儚錛?/span>(d) DCPNAs鐨?/span>XRD鍥捐氨錛?/span>(e) DCPNAs鐨?/span>XPS鍏ㄥ浘璋憋紱(f) DCPNAs鐨?/span>O 1s XPS楂樺垎杈ㄨ氨錛?/span>(g) DCPNAs鐨?/span>Cu 2p XPS楂樺垎杈ㄨ氨
Figure 2. (a)閫氳繃TMB鏄捐壊媯嫻?/span>DCPNAs鍦ㄤ笉鍚?/span>pH鍊間笅鐨勫偓鍖栨ц兘錛?/span>(b)閲囩敤DCFH媯嫻嬩笉鍚?/span>pH鍊間笅DCPNAs鐨?/span>ROS鐢熸垚錛屾彃鍥炬樉紺?/span>ROS鐢熸垚鐨勭櫨鍒嗘瘮錛?/span>鍦ㄤ笉鍚?/span>pH鍊?/span>涓嬬敤涓嶅悓嫻撳害DCPNAs澶勭悊鐨?/span>(c) 閲戦粍鑹茶憽钀勭悆鑿屽拰(d) 娌欓棬姘忚弻鐨勭粏鑿屽瘑搴?/span>錛?/span>(e) 鍦ㄤ笉鍚?/span>pH鍊間笅緇忚繃鍜屾湭緇忚繃DCPNAs澶勭悊鐨勯噾榛勮壊钁¤悇鐞冭弻鍜屾矙闂ㄦ皬鑿岀殑緇嗚弻鑿岃惤鐢熼暱鍥懼儚錛?/span>(f) 鍦ㄤ笉鍚?/span>pH鍊?/span>涓嬬粡榪囧拰鏈粡DCPNAs澶勭悊鐨勯噾榛勮壊钁¤悇鐞冭弻鍜屾矙闂ㄦ皬鑿岀殑SEM鍥懼儚
Figure 3. (a) 閲戦粍鑹茶憽钀勭悆鑿屽拰 (b) 娌欓棬姘忚弻鍦ㄤ笉鍚?pH 鍊間笅緇忚繃鍜屾湭緇?/span>DCPNAs澶勭悊鐨勭敓鐗╄啘鐢熺墿閲?/span> (n = 3, * P < 0.05)錛?/span>(c) 鍦?/span> pH 7.4錛?/span>I-1 / II-1錛夛紝pH 6.5錛?/span>I-2 / II-2錛夊拰 pH 5.6錛?/span>I-3 / II -3錛変笅鏈粡DCPNAs澶勭悊錛?/span>I -1-I -3錛夊拰緇忚繃DCPNAs澶勭悊錛?/span>II -1-II -3錛夌殑閲戦粍鑹茶憽钀勭悆鑿屽拰娌欓棬姘忚弻鐨勭敓鐗╄啘緇撴櫠绱煋鑹?/span>鍥撅紱(d) 鍦ㄤ笉鍚?/span>pH鍊間笅DCPNAs鎶戝埗鍚庣敓鐗╄啘鐨?/span>3D CLSM鍥懼儚錛屾媿鎽勭殑鍥懼儚鍖哄煙澶у皬涓?/span>1270 渭m × 1270 渭m錛?/span>(e) DCPNAs鍦ㄥ畬鏁寸敓鐗╄啘涓殑鍌寲鎬ц兘錛堢┖鐧芥槸鏈粡澶勭悊鐨勭敓鐗╄啘錛夈?/span> (f) 鍩轟簬MTT嫻嬪畾鐨?/span>DCPNAs鐮村潖鐢熺墿鑶滅殑浣滅敤
Figure 4. DCPNAs鍦ㄦ不鐤楃粏鑿屾劅鏌撴у垱闈腑鐨勫簲鐢ㄨ瘯楠岀粨鏋滐細(a) DCPNAs澶勭悊浼ゅ彛鍒涢潰紺烘剰鍥撅紱(b) 鍚勭粍浼ゅ彛鍒涢潰鍙樺寲鍥撅紱(c) DCPNAs瀵逛激鍙ｈ〃闈㈢粏鑿岀殑鎶楄弻鏁堟灉鍥撅紱(d) 鍚勭粍浼ゅ彛闈㈢Н闅忔椂闂村彉鍖栫洿鏂瑰浘(* P <0.05)錛?/span>(e) DCPNA瀵逛激鍙ｈ〃闈㈢粏鑿岀殑鎶楄弻鏁堟灉錛?/span>(f) 娌葷枟9 d鏃跺悇緇勭殑灝忛紶浼ゅ彛緇勭粐鐨?/span>H&E鏌撹壊鍒囩墖緇撴灉
Figure 5. 娌葷枟9 d鏃跺悇緇勭殑灝忛紶涓昏鍣ㄥ畼鐨?/span>H&E鏌撹壊鍒囩墖緇?/span>
瑗垮寳鍐滄灄縐戞妧澶у椋熷搧縐戝涓庡伐紼嬪闄㈢澹瘯涓氱敓鏉庢晱涓鴻璁烘枃鐨勭涓浣滆咃紝鍏卞悓閫氳浣滆呬負鐜嬪緩榫欐暀鎺堬紝寮犳枃娑涘壇鏁欐巿銆?/span>
浣滆呯畝浠?/span>
鐜嬪緩榫欙紝鐢鳳紝1979騫寸敓錛屽崥澹紝鏁欐巿錛屽崥澹敓瀵煎笀錛岃崳鑾峰浗鍔￠櫌鏀垮簻鐗規畩媧ヨ創錛屽叆閫夐檿瑗跨渷鍒涙柊浜烘墠鎺ㄨ繘璁″垝涓潚騫寸鎶鍒涙柊棰嗗啗浜烘墠錛岃崳鑾烽檿瑗跨渷鏉板嚭闈掑勾鍩洪噾璧勫姪錛屽叆閫夋暀鑲查儴鏂頒笘綰紭縐浜烘墠錛岄檿瑗跨渷闈掑勾縐戞妧鏂版槦錛屽叆閫夎嫳鍥界殗瀹跺寲瀛︿細銆?/span>Top 1%楂樿寮曚腑鍥戒綔鑰呫忔鍗曘?/span>鏈熷垔Foods緙栧錛?/span>銆婇鍝佺爺絀朵笌寮鍙戙嬬紪濮旓紝銆婂垎鏋愭祴璇曞鎶ャ嬮潚騫寸紪濮?/span>銆傝崳鑾?/span>闄曡タ鐪侀珮絳夊鏍＄瀛︽妧鏈涓絳夊錛?/span>闄曡タ鐪侀潚騫寸鎶濂栵紝闄曡タ鐪佽嚜鐒剁瀛︿紭縐瀛︽湳璁烘枃濂栥傜編鍥藉寲瀛︿細銆佺編鍥借嚜鍔ㄥ寲涓庣瓫閫夊崗浼氥佷腑鍥藉寲瀛︿細浼氬憳錛?/span>Advanced Functional Materials銆?/span>Biosensor & Bioelectronics銆侀鍝佽川閲忔嫻嬪鎶ョ瓑鍥藉唴澶栬憲鍚嶆湡鍒婂紼夸漢銆?/span>
寮犳枃娑涳紝鐢鳳紝鍗氬＋錛屽壇鏁欐巿錛屽崥澹敓瀵煎笀錛?/span>鍏堝悗鍏ラ?/span>鈥?span style="font-family:瀹嬩綋;">鍗氬＋鍚庡垱鏂頒漢鎵嶆敮鎸佽鍒?/span>鈥?/span>銆?/span>鈥?/span>闄曡タ鐪侀珮鏍＄鍗忛潚騫翠漢鎵嶆墭涓捐鍒?/span>鈥?/span>銆?/span>鈥?/span>浠茶嫳闈掑勾瀛﹁?/span>鈥?/span>銆?/span>涓昏浠庝簨鍩轟簬綰崇背鎶鏈殑椋熷搧瀹夊叏鍥犲瓙蹇熸嫻嬪拰楂樻晥鎺у埗鎶鏈爺絀跺伐浣溿備富鎸佸浗瀹惰嚜鐒剁瀛﹀熀閲戦潚騫撮」鐩佸崥澹悗縐戝鍩洪噾闈笂欏圭洰涓絳夎祫鍔┿侀檿瑗跨渷閲嶇偣鐮斿彂璁″垝絳夐」鐩紝鑽ｈ幏涓浗鍗氬＋鍚庡垱鏂頒漢鎵嶆敮鎸佽鍒掑崄澶у垱鏂版垚鏋溿侀檿瑗塊珮絳夊鏍＄瀛︽妧鏈竴絳夊錛?/span>闄曡タ鐪佽嚜鐒剁瀛︿紭縐瀛︽湳璁烘枃濂?/span>銆?br />
璇鵑緇勭綉鍧錛?br /> https://www.x-mol.com/groups/wang_jianlong
鐩稿叧閾炬帴
https://doi.org/10.1021/acsami.1c03409